業績

論文発表等

2023年

Kenji Okamoto & Yasushi Sako
"Two closed conformations of CRAF require the 14-3-3 binding motifs and cysteine-rich domain to be intact in live cells"
J. Mol. Biol., 2023, vol. 435, 167989.
https://doi.org/10.1016/j.jmb.2023.167989

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2022年

Kenji Okamoto & Yasushi Sako
"Two closed conformations of CRAF require the 14-3-3 binding motifs and cysteine-rich domain to be intact in live cells"
bioRxiv, 2022.
https://doi.org/10.1101/2022.10.21.513144
Yukinobu Arata, Itsuki Shiga, Yusaku Ikeda, Peter Jurica, Hiroshi Kimura, Ken Kiyono & Yasushi Sako
"Insulin signaling shapes fractal scaling of C. elegans behavior"
Sci. Reports, 2022, vol. 12, 10481.
https://doi.org/10.1038/s41598-022-13022-6
Press Release (in Japanese)
Yoshiko Nakagawa, Howard C.-H. Shen, Yusuke Komi, Shinju Sugiyama, Takaaki Kurinomaru, Yuri Tomabechi, Elena Krayukhina, Kenji Okamoto, Takeshi Yokoyama, Mikako Shirouzu, Susumu Uchiyama, Megumi Inaba, Tatsuya Niwa, Yasushi Sako, Hideki Taguchi & Motomasa Tanaka
"Amyloid conformation-dependent disaggregation in a reconstituted yeast prion system"
Nat. Chem. Biol., 2022, vol. 18, pp.321-331.
https://doi.org/10.1038/s41589-021-00951-y
Wooseok Heo, Kazuto Hasegawa, Kenji Okamoto, Yasushi Sako, Kunihiko Ishii, and Tahei Tahara
"Scanning Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy: Conformational Dynamics of DNA Holliday Junction from Microsecond to Subsecond"
J. Phys. Chem. Lett. 2022, vol. 13, pp.1249–1257.
https://doi.org/10.1021/acs.jpclett.1c03787
Kouki Kawakami, Masataka Yanagawa, Suzune Hiratsuka, Misaki Yoshida, Yuki Ono, Michio Hiroshima, Masahiro Ueda, Junken Aoki, Yasushi Sako, Asuka Inoue
"Heterotrimeric Gq proteins act as a switch for GRK5/6 selectivity underlying β-arrestin transducer bias"
Nature Communications 13(1) 2022
DOI: 10.1038/s41467-022-28056-7

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2021年

Yukinobu Arata, Itsuki Shiga, Yusaku Ikeda, Peter Jurica, Hiroshi Kimura, Ken Kiyono, Yasushi Sako
“Fractal scaling of C. elegans behavior is shaped by insulin signaling”
biorxiv 2021
https://doi.org/10.1101/2021.12.02.471007
柳川正隆, 佐甲靖志
「Gタンパク質共役型受容体の生細胞1分子計測を薬効薬理評価に応用する」生物物理 61(6) 366-369 2021
DOI: 10.2142/biophys.61.366
Ryo Yoshizawa, Nobuhisa Umeki, Akihiro Yamamoto, Mariko Okada, Masayuki Murata, and Yasushi Sako.
“p52Shc regulates the sustainability of ERK activation in a RAF-independent manner”.
Molecular Biology of the Cell, Vol. 32, No. 19, pp. 1838-1848, Sep 1, 2021
https://doi.org/10.1091/mbc.e21-01-0007
Ryo Yoshizawa, Nobuhisa Umeki, Akihiro Yamamoto, Masayuki Murata, and Yasushi Sako.
“Biphasic spatiotemporal regulation of GRB2 dynamics by p52SHC for transient RAS activation”.
Biophysics and Physicobiology, Vol. 18, pp. 1-12, Jan 5, 2021
https://doi.org/10.2142/biophysico.bppb-v18.001
Mitsuhiro Abe, Asami Makino, Motohide Murate, Françoise Hullin-Matsuda, Masataka Yanagawa, Yasushi Sako, Toshihide Kobayashi
"PMP2/FABP8 induces PI(4,5)P2-dependent transbilayer reorganization of sphingomyelin in the plasma membrane"
Cell Reports 37(6) 109935-109935 2021
DOI: 10.1016/j.celrep.2021.109935
Keiichi Kojima, Yuki Matsutani, Masataka Yanagawa, Yasushi Imamoto, Yumiko Yamano, Akimori Wada, Yoshinori Shichida, Takahiro Yamashita
"Evolutionary adaptation of visual pigments in geckos for their photic environment" Science Advances 7(40) 2021
DOI: 10.1126/sciadv.abj1316
Momoko Akiyama, Ryosuke Ueki, Masataka Yanagawa, Mitsuhiro Abe, Michio Hiroshima, Yasushi Sako, Shinsuke Sando
"DNA-Based Synthetic Growth Factor Surrogates with Fine-Tuned Agonism" Angewandte Chemie International edition
https://doi.org/10.1002/anie.202105314
Yutaro Kuwashima, Masataka Yanagawa, Mitsuhiro Abe, Michio Hiroshima, Masahiro Ueda, Makoto Arita and Yasushi Sako
"Comparative Analysis of Single-Molecule Dynamics of TRPV1 and TRPV4 Channels in Living Cells" Int. J. Mol. Sci. 2021, 22(16), 8473;
https://doi.org/10.3390/ijms22168473
Michio Hiroshima, Yasushi Sako
In-Cell Single-Molecule Analysis of Molecular State and Reaction Kinetics Coupling Pages 59-80
Advanced Imaging and Bio Techniques for Convergence Science. Editors
Jun Ki Kim, Jeon Kon Kim, Chan-Gi Pack
https://link.springer.com/book/10.1007/978-981-33-6064-8
Mitsuhiro Abe, Toshihide Kobayashi
Imaging Sphingomyelin- and Cholesterol-Enriched Domains in the Plasma Membrane Using a Novel Probe and Super-Resolution Microscopy
Pages 81-90
Advanced Imaging and Bio Techniques for Convergence Science. Editors
Jun Ki Kim, Jeon Kon Kim, Chan-Gi Pack
https://link.springer.com/book/10.1007/978-981-33-6064-8
柳川正隆, 佐甲靖志
「GPCRの細胞内1分子イメージング」
月刊「細胞」2021年 5月号
https://bit.ly/3vDrDT5
Yanagawa M., Sako Y.
"Workflows of the Single-Molecule Imaging Analysis in Living Cells: Tutorial Guidance to the Measurement of the Drug Effects on a GPCR."
(2021) In: Kim SB. (eds) Live Cell Imaging. Methods in Molecular Biology, vol 2274. Humana, New York, NY.
doi: https://doi.org/10.1007/978-1-0716-1258-3_32

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2020年

廣島通夫
「AIにより実現した細胞内1分子動態の大規模網羅的イメージング」
日本化学会情報化学部会誌（CICSJ Bulletin） 2020年 38巻 pp.12-15
DOI:10.11546/cicsj.38.12
Hiraku Miyagi, Michio Hiroshima,and Yasushi Sako
"Cell-to-cell diversification in ERBB-RAS-MAPK signal transduction that produces cell-type specific growth factor responses"
Biosystems 199 104293 (2021)
doi: 10.1016/j.biosystems.2020.104293
岡本憲二
「1分子計測データの隠れ状態を推定する統計的解析法―隠れマルコフモデルと最大エントロピー-クラスタリング」
実験医学増刊 Vol.38 No.20「機械学習を生命科学に使う！」
第4章　統計解析、Ⅱ．動態・状態解析 3．
Yusaku Ikeda, Peter Jurica, Hiroshi Kimura, Hiroaki Takagi, Struzik
Zbigniew, Ken Kiyono, Yukinobu Arata, and Yasushi Sako
"C. elegans episodic swimming is driven by multifractal kinetics"
Scientific Reports
doi: 10.1038/s41598-020-70319-0
Michio Hiroshima, Masato Yasui, and Masahiro Ueda
"Large-scale single-molecule imaging aided by artificial intelligence"
Microscopy
doi:10.1093/jmicro/dfz116 (Invited review article)
Yukinobu Arata, Taku Oshima, Yusaku Ikeda, Hiroshi Kimura and Yasushi Sako
"OP50, a bacterial strain conventionally used as food for laboratory maintenance of C. elegans, is a biofilm formation defective mutant"
microPublication Biology
doi:10.17912/micropub.biology.000216
Kenji Okamoto, Kayo Hibino, and Yasushi Sako
"In-cell single-molecule FRET measurements reveal three conformational state changes in RAF protein"
Biochimica et Biophysica Acta (BBA) - General Subjects. 2020, 1864 (2), 129358
(Publication Date (Web): May 7, 2019)
doi: 10.1016/j.bbagen.2019.04.022

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2019年

Makiko Sato, Haruka Aoki-Saito, Hayato Fukuda, Hiroyuki Ikeda, Yasuhiko Koga, Masakiyo Yatomi, Hiroaki Tsurumaki, Toshitaka Maeno, Tsugumichi Saito, Takashi Nakakura, Tetsuya Mori, Masataka Yanagawa, Mitsuhiro Abe, Yasushi Sako, Kunio Dobashi, Tamotsu Ishizuka, Masanobu Yamada, Satoshi Shuto, and Takeshi Hisada
"Resolvin E3 attenuates allergic airway inflammation via the interleukin-23–interleukin-17A pathway"
FASEB J. 2019 Nov;33(11):12750-12759.
doi: 10.1096/fj.201900283R
Yukinobu Arata, and Hiroaki Takagi
"Quantitative Studies for Cell-division Cycle Control "
Front. Physiol., 19 August 2019
doi: 10.3389/fphys.2019.01022
Kenji Okamoto, and Yasushi Sako
"Single-Molecule Förster Resonance Energy Transfer Measurement Reveals the Dynamic Partially Ordered Structure of the Epidermal Growth Factor Receptor C-Tail Domain"
J. Phys. Chem. B. 2019, 123 (3), pp 571–581
(Publication Date (Web): December 20, 2018)
doi: 10.1021/acs.jpcb.8b10066

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2018年

廣島通夫，上田昌宏
「生きてるものは全部観る！　イメージングの選び方・使い方100＋」
実験医学増刊 Vol.36 No.20 (2018年12月03日発行)
「第4章　超解像顕微鏡　33．PALM/STORM」
Keita Sato, Takahiro Yamashita, Keiichi Kojima, Kazumi Sakai, Yuki Matsutani, Masataka Yanagawa, Yumiko Yamano, Akimori Wada, Naoyuki Iwabe, Hideyo Ohuchi, and Yoshinori Shichida
"Pinopsin evolved as the ancestral dim-light visual opsin in vertebrates"
Communications Biology. 2018, Oct. 1;1(156)
doi: 10.1038/s42003-018-0164-x
Masataka Yanagawa, Michio Hiroshima, Yuichi Togashi, Mitsuhiro Abe, Takahiro Yamashita, Yoshinori Shichida, Masayuki Murata, Masahiro Ueda, and Yasushi Sako
"Single-molecule diffusion-based estimation of ligand effects on G protein–coupled receptors"
Sci. Signal. 2018, Sep 18;11(548):eaao1917.
doi: 10.1126/scisignal.aao1917

The toll free refer links [ Summary, Abstract, Reprint (pdf), Full text]

(You can freely access the published version of the manuscript without going through the Member Login screen of Science Signaling from the links above.)
Masato Yasui, Michio Hiroshima, Jun Kozuka, Yasushi Sako, and Masahiro Ueda
"Automated single-molecule imaging in living cells"
Nat Commun. 2018, Aug 3;9(1):3061.
doi: 10.1038/s41467-018-05524-7
Yuki Shindo, Yohei Kondo, and Yasushi Sako
"Inferring a nonlinear biochemical network model from a heterogeneous single-cell time course data"
Sci. Rep. 8. 6790, (2018).
doi: 10.1038/s41598-018-25064-w
Ryo Maeda, Michio Hiroshima, Takahiro Yamashita, Akimori Wada, Yasushi Sako, Yoshinori Shichida, and Yasushi Imamoto
"Shift in Conformational Equilibrium Induces Constitutive Activity of G-Protein-Coupled Receptor, Rhodopsin"
J. Phys. Chem. B, 2018, 122 (18), pp 4838–4843 (2018).
doi: 10.1021/acs.jpcb.8b02819
Michio Hiroshima, Chan-gi Pack, Kazunari Kaizu, Koichi Takahashi, Masahiro Ueda, and Yasushi Sako
"Transient acceleration of epidermal growth factor receptor dynamics produces higherorder signaling clusters"
Journal of Molecular Biology 430(9) pp.1381-1396 (2018).
doi: 10.1016/j.jmb.2018.02.018
Shigeyuki Magi, Kazunari Iwamoto, Noriko Yumoto, Michio Hiroshima, Takeshi Nagashima, Rieko Ohki, Amaya Garcia-Munoz, Natalia Volinsky, Alexander Von Kriegsheim, Yasushi Sako, Koichi Takahashi, Shuhei Kimura, Boris N. Kholodenko, and Mariko Okada-Hatakeyama
"Transcriptionally inducible Pleckstrin homology-like domain, family A, member 1, attenuates ErbB receptor activity by inhibiting receptor oligomerization"
J. Biol. Chem. 293, 2206-2218 (2018).
doi: 10.1074/jbc.M117.778399
Ryo Maeda, Takeshi Sato, Kenji Okamoto, Masataka Yanagawa, and Yasushi Sako
"Lipid-protein interplay in dimerization of the juxtamembrane domains of epidermal growth factor receptor"
Biophysical Journal, Vol. 114, pp.893-903 (2018).
doi:10.1016/j.bpj.2017.12.029
Ryota Iino, Tatsuya Iida, Akihiko Nakamura, Ei-ichiro Saita, Huijuan Youd, Yasushi Sako
"Single-molecule imaging and manipulation of biomolecular machines and systems"
Biochem. Biophys. Acta. General Subjects, 1862, 241-252. (2018). (Review)
doi: 10.1016/j.bbagen.2017.08.008

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2017年

Kenji Okamoto, Michio Hiroshima, Yasushi Sako
"Single-molecule fluorescence-based analysis of protein conformation, interaction, and oligomerization in cellular systems"
Biophysical Reviews (2017).
doi:10.1007/s12551-017-0366-3
Yuki Nakamura, Nobuhisa Umeki, Mitsuhiro Abe & Yasushi Sako
"Mutation-Specific Mechanisms of Hyperactivation of Noonan Syndrome SOS Molecules Detected with Single-molecule Imaging in Living Cells"
Sci. Reports, Vol. 7:14153 (2017).
doi: 10.1038/s41598-017-14190-6
Mariko Sumi, Asami Makino, Takehiko Inaba, Yasushi Sako, Fumihiro Fujimori, Peter Greimel, and Toshihide Kobayashi
"Photoswitchable phospholipid FRET acceptor: Detergent free intermembrane transfer assay of fluorescent lipid analogs "
Sci Report, Vol. 7:2900 (2017).
[doi: 10.1038/s41598-017-02980-x]
Ryo Yoshizawa, Nobuhisa Umeki, Masataka Yanagawa, Masayuki Murata, and Yasushi Sako
"Single-molecule fluorescence imaging of RalGDS on cell surfaces during signal transduction from Ras to Ral. "
Biophys Physicobiol., Vol. 14:75-84 (2017).
[doi: 10.2142/biophysico.14.0_75]
Keiichi Kojima, Yuki Matsutani, Takahiro Yamashit, Masataka Yanagawa, Yasushi Imamoto, Yumiko Yamano, Akimori Wada, Osamu Hisatomi, Kanto Nishikawae, Keisuke Sakurai, and Yoshinori Shichida
"Adaptation of cone pigments found in green rods for scotopic vision through a single amino acid mutation "
PNAS Vol.114, 5437-5442 (2017).
[doi: 10.1073/pnas.1620010114]
Kenji Okamoto and Yasushi Sako
"Recent advances in FRET for the study of protein interactions and dynamics"
Current Opinion in Structural Biology Volume 46, 16-23 (2017). [doi: 10.1016/j.sbi.2017.03.010]
Kenji Okamoto
"Analyzing Single Molecule FRET Trajectories Using HMM"
"Hidden Markov Models" Methods in Molecular Biology Series, vol.1552 Chapter 7, p103-113, Springer (2017)

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2016年

Yuki Nakamura, Kayo Hibino, Toshio Yanagida, Yasushi Sako
"Switching of the positive feedback for RAS activation by a concerted function of SOS membrane association domains"
Biophysics and Physicobiology, 2016 vol 13, 1-11 Open Access
Yukinobu Arata*, Michio Hiroshima, Chan-Gi Pack, Ravikrishna Ramanujam, Fumio Motegi, Kenichi Nakazato, Yuki Shindo, Paul W. Wiseman, Hitoshi Sawa, Tetsuya J. Kobayashi, Hugo B. Brandao, Tatsuo Shibata, and Yasushi Sako*
"Cortical Polarity of the RING Protein PAR-2 is Maintained by Exchange Rate Kinetics at the Cortical-Cytoplasmic Boundary"
Cell Reports (2016). 16. 8 pp 2156-2168,
[doi: http://dx.doi.org/10.1016/j.celrep.2016.07.047]
An art image was introduced as a slider image on the Cell Reports website.
Yuki Shindo, Kazunari Iwamoto, Kazunari Mouri, Kayo Hibino, Masaru Tomita, Hidetaka Kosako, Yasushi Sako, and Koichi Takahashi
"Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling"
Nature Communications 7, Article number: 10485 (2016), pp. 21-27
[doi:10.1038/ncomms10485] Open Access
Kenji Okamoto, and Yasushi Sako.
"State transition analysis of spontaneous branch migration of the Holliday junction by photon-based single-molecule fluorescence resonance energy transfer"
Biophysical Chemistry (2016), pp. 21-27
[doi:10.1016/j.bpc.2015.11.004] Open Access

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2015年

佐甲靖志
「光学顕微鏡技術の過去・現在・未来」
生物物理, 2015, 55:317–175.
[link]
Yanagawa M, Kojima K, Yamashita T, Imamoto Y, Matsuyama T, Nakanishi K, Yamano Y, Wada A, Sako Y, and Shichida Y.
"Origin of the low thermral isomerization rate of rhodopsin chromophore"
Scientific Reports. 2015, 5:11081.
[doi:10.1038/srep11081] Open Access
Takanezawa S, Morita S, Ozaki Y, and Sako Y.
"Raman spectral dynamics of single cells in the early stages of growth factor stimulation"
Biophys J. 2015, 108(9):2148-57.
[doi:10.1016/j.bpj.2015.03.037]
Arata Y, Takagi H, Sako Y, and Sawa H.
"Power law relationship between cell cycle duration and cell volume in the early embryonic development of Caenorhabditis elegans"
Front Physiol. 2015, 5:529.
[doi:10.3389/fphys.2014.00529]
この論文は、2015年にFrontiers journal seriesから出版された12,500本の論文の内、最も閲覧された論文の16位にノミネートされました。
Park H., Han S.S., Sako Y., and Pack C.G.,
"Dynamic and unique nucleolar microenvironment revealed by fluorescence correlation spectroscopy"
FASEB J. 2015, 29(3):837-48.
[doi:10.1096/fj.14-254110. ]

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2014年

岡本憲二
「１分子計測実験から分子状態を識別する統計的データ解析」
統計数理, 2014, 62:257–272.
[link]
Shin-ichi Morita, Sota Takanezawa, Michio Hiroshima, Toshiyuki Mitsui, Yukihiro Ozaki, and Yasushi Sako
"Raman and Autofluorescence Spectrum Dynamics along the HRG-Induced Differentiation Pathway of MCF-7 Cells"
Biophysical Journal, 2014, 107; 2221–2229
[doi:10.1016/j.bpj.2014.10.002]
岡本憲二
「生命科学のための蛍光分光第 4 回蛍光分子の動的過程の解析 1 (一分子蛍光計測)」
分光研究, 2014, 63:165–175.
[link]
佐甲靖志、廣島通夫、日比野佳代
"細胞内情報処理反応の1分子計測：タンパク質ダイナミクスと分子認識"
1分子ナノバイオ計測: 分子から生命システムを探る革新的技術. １４章
Hisaaki Shinohara, Marcelo Behar, Kentaro Inoue, Michio Hiroshima, Tomoharu Yasuda, Takeshi Nagashima, Shuhei Kimura, Hideki Sanjo, Shiori Maeda, Noriko Yumoto, Sewon Ki, Shizuo Akira, Yasushi Sako, Alexander Hoffmann, Tomohiro Kurosaki, and Mariko Okada-Hatakeyama
"Positive Feedback Within a Kinase Signaling Complex Functions as a Switch Mechanism for NF-κB Activation"
Science, 2014, 344; 760–764.
[doi:10.1126/science.1250020]
Press Release (in Japanese)
Vitaly Kochin, Takeshi Shimi, Elin Torvaldson, Stephen A. Adam, Anne Goldman, Chan-Gi Pack, Johanna Melo-Cardenas, Susumu Y. Imanishi, Robert D. Goldman, and John E. Eriksson
"Interphase phosphorylation of lamin A"
Journal of Cell Science, 2014, 127; 2683–2696.
[doi:?10.1242/jcs.141820]
Chan-Gi Pack, Min-Kyo Jung, Mi-Roung Song, Jun-Sung Kim, Sung-Sik Han, and Yasushi Sako
"Use of Engineered Nanoparticle-Based Fluorescence Methods for Live-Cell Phenomena"
Fluorescence Microscopy: Super-Resolution and Other Novel Techniques, Chapter 11, Elsevier.
[doi:?10.1016/B978-0-12-409513-7.00011-7]]
Chan-Gi Pack, Haruka Yukii, Akio Toh-e, Tai Kudo, Hikaru Tsuchiya, Ai Kaiho, Eri Sakata, Shigeo Murata, Hideyoshi Yokosawa, Yasushi Sako, Wolfgang Baumeister, Keiji Tanaka, and Yasushi Saeki
"Quantitative live-cell imaging reveals spatio-temporal dynamics and cytoplasmic assembly of the 26S proteasome"
Nature Communications, 2014, 5; Article number: 3396.
[doi:10.1038/ncomms4396]
Press Release (in Japanese)
Jaeran Lee, Fumihiko Fujii, Soo Yong Kim, Chan-Gi Pack, and Sok Won Kim
"Analysis of Quantum Rod Diffusion by Polarized Fluorescence Correlation Spectroscopy"
J. Fluorescence, 2014; 1–8.
[doi:10.1007/s10895-014-1367-2]
Ryo Maeda, Michio Hiroshima, Takahiro Yamashita, Akimori Wada, Shoko Nishimura, Yasushi Sako, Yoshinori Shichida, and Yasushi Imamoto
"Single-Molecule Observation of the Ligand-Induced Population Shift of Rhodopsin, A G-Protein-Coupled Receptor"
Biophys. J., 2014, 106 (4); 915–924.
[doi:10.1016/j.bpj.2014.01.020]

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2013年

廣島通夫、佐甲靖志
「1分子キネティクス解析により示されたErbB受容体の反応調節機構」
生物物理, 2013, Vol. 53, No. 6, 317–318.
Hayashi K., Pack C.G., Sato MK, Mouri K., Kaizu K., Takahashi K. and Okada Y.
"Viscosity and drag force involved in organelle transport: Investigation of the fluctuation dissipation theorem"
Eur. Phys. J. E, 2013, 36 (12); 136.
[doi:10.1140/epje/i2013-13136-6]
Highlight: link / cover: link
S. Ohta, S. Kawai-Noma, A. Kitamura, C-G. Pack, M. Kinjo, and H. Taguchi
"Interaction of Hsp104 with yeast prion Sup35 analyzed by fluorescence cross-correlation spectroscopy"
Biochem. Biophys. Res. Commun., 2013, 442 (1–2); 28–32.
[doi:10.1016/j.bbrc.2013.10.147]
J. Lee, F. Fujii, S. Y. Kim, C. G. Back, S. and K. Kim
"Study on the diffusions of a quantum rod using polarized fluorescence correlation spectroscopy"
Proc. SPIE 8879, Nano-Bio Sensing, Imaging, and Spectroscopy, 2013, 88790R.
[doi:10.1117/12.2018690]
Sota Takanezawa, Yasushi Sako, Yukihiro Ozaki, and Shin-ichi Morita
"Mechanism of sequential order determination in bio-Raman correlation analysis"
Proc. SPIE 8879, Nano-Bio Sensing, Imaging, and Spectroscopy, 2013, 887902.
[doi:10.1117/12.2018723]
Sota Takanezawa, Akinori Baba, Yasushi Sako, Yukihiro Ozaki, Akira Date; Kazumi Toyama, and Shin-ichi Morita
"Image enhancement of optical images for binary system of melanocytes and keratinocytes"
Proc. SPIE 8879, Nano-Bio Sensing, Imaging, and Spectroscopy, 2013, 88790I.
[doi:10.1117/12.2018681]
Jun-ichi Ishihara, Masashi Tachikawa, Atsushi Mochizuki, Yasushi Sako, Hideo Iwasaki, and Shin-ichi Morita
"Raman imaging of the diverse states of the filamentous cyanobacteria"
Proc. SPIE 8879, Nano-Bio Sensing, Imaging, and Spectroscopy, 2013, 88790V.
[doi:10.1117/12.2018694]
Shin-ichi Morita, Sota Takanezawa, Akira Date, Shin Watanabe, and Yasushi Sako
"Raman Spectroscopic Analysis of H₂O₂-Stimulated Three-Dimensional Human Skin Models Containing Asian, Black, and Caucasian Melanocytes"
Journal of Spectroscopy, 2013, 2013; Article ID 903450.
[doi:10.1155/2013/903450]
Chie Arai, Hiroshi Kurahashi, Chan-Gi Pack, Yasushi Sako, and Yoshikazu Nakamura
"Clearance of yeast eRF-3 prion [PSI+] by amyloid enlargement due to the imbalance between chaperone Ssa1 and cochaperone Sgt2"
Translation, 2013, 1 (2); eLocation ID:26574.
[link / doi: 10.4161/trla.26574]
Kazunari Mouri, and Yasushi Sako
"Optimality conditions for cell-fate heterogeneity that maximize the effects of growth factors in PC12 cells"
PLOS Computational Biology, 2013, 9 (11); e1003320.
[doi:10.1371/journal.pcbi.1003320]
Kyunghee Byun, Taek-Kyun Kim, Jeehyun Oh, Enkhjargal Bayarsaikhan, Daesik Kim, Min Young Lee, Chan-Gi Pack, Daehee Hwang, and Bonghee Lee
"Heat shock instructs hESCs to exit from the self-renewal program through negative regulation of OCT4 by SAPK/JNK and HSF1 pathway"
Stem Cell Research, 2013, 11 (3); 1323–1334.
[doi:10.1016/j.scr.2013.08.014]
Masakazu Iwai, Chan-Gi Pack, Yoshiko Takenaka, Yasushi Sako, and Akihiko Nakano
"Photosystem II antenna phosphorylation-dependent protein diffusion determined by fluorescence correlation spectroscopy"
Scientific Reports, 2013, 3; Article number: 2833.
[doi:10.1038/srep02833]
Kenji Okamoto
"Introduction of FRET Application to Biological Single-molecule Experiments"
International Journal of Biophysics, 2013, 3 (1A); 9–17.
[doi:10.5923/s.biophysics.201311.02]
Tadasu Nozaki, Kazunari Kaizu, Chan-Gi Pack, Sachiko Tamura, Tomomi Tani, Saera Hihara, Takeharu Nagai, Koichi Takahashi, and Kazuhiro Maeshima
"Flexible and dynamic nucleosome fiber in living mammalian cells"
Nucleus, 2013, 4 (5); 349–356; PMID: 23945462.
[doi:10.4161/nucl.26053]
Kayo Hibino, Michio Hiroshima, Yuki Nakamura, and Yasushi Sako
"Single-Molecule Imaging Measurements of Protein-Protein Interactions in Living Cells"
An Integrated View of the Molecular Recognition and Toxinology — From Analytical Procedures to Biomedical Applications, Chapter 17, pp. 432–453.
[doi:10.5772/52386]
Naoko Abe, Michio Hiroshima, Hideto Maruyama, Yuko Nakashima, Yukiko Nakano, Akira Matsuda, Yasushi Sako, Yoshihiro Ito, and Hiroshi Abe
"Rolling circle amplification in a prokaryotic translation system using small circular RNA"
Angewandte Chemie International Edition, 2013, 52 (27); 7004–7008. [doi:10.1002/anie.201302044]
Press Release: Japanese / English
KiYoung Lee, Kyunghee Byun, Wonpyo Hong, Han-Yu Chuang, Chan-Gi Pack, Enkhjargal Bayarsaikhan, Sun Ha Paek, Hyosil Kim, Hye Young Shin, Trey Ideker, and Bonghee Lee
"Proteome-wide discovery of mislocated proteins in cancer"
Genome Research, 2013, 23 (8); 1283–1294.
[doi:10.1101/gr.155499.113]
山本明弘、廣島通夫、佐甲靖志
「Localization Microscopy の原理と受容体イメージングへの応用」
光技術コンタクト, 2013, Vol. 51, No. 4, 33–40.
Keita Oishi, Hiroshi Kurahashi, Chan-Gi Pack, Yasushi Sako, and Yoshikazu Nakamura
"A bipolar functionality of Q/N-rich proteins: Lsm4 amyloid causes clearance of yeast prions"
MicrobiologyOpen, 2013, 2 (3); 415–430.
[doi:10.1002/mbo3.83]
Hyo-Sup Shin, Akimitsu Okamoto, Yasushi Sako, Sok Won Kim, Soo Yong Kim, and Chan-Gi Pack* (C.G Pack is the corresponding author)
"Characterization of Triplet State of Hybridization-Sensitive DNA Probe by Using Fluorescence Correlation Spectroscopy"
The Journal of Physical Chemistry A, 2013, 117; 27–33.
[doi:10.1021/jp307018k]
廣島通夫、佐甲靖志
「超解像顕微鏡の世界：波長の壁を超えて見る(2) 受容体イメージング」
現代化学, 2013, 503, 56–57.

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2012年

Hiroko Miyamoto, Itsushi Minoura, Kenji Okamoto, Yoshiyuki Takizawa, and Masahiro Teshima
"SiPM interdisciplinary application in the fields of astroparticle physics and bio-molecular science"
Nuclear Instruments and Methods in Physics Research Section A, 2012, vol. 695, 87–90.
[doi:10.1016/j.nima.2011.11.078]
Hihara S. & Pack C.G (HS and PCG contributed equally to this paper), Kaizu K., Tani T., Hanfusa T., Nozaki T., Takemoto S., Yoshimi T., Yokota H., Imamaoto N., Sako Y., Kinjo M., Takahashi K., Nagai T., and Maeshima K.*
“Local nucleosome dynamics facilitate chromatin accessibility in living mammalian cells”
Cell Reports, 2012, 2; 1645–1656.
[doi:10.1016/j.celrep.2012.11.008]
Press Release: Japanese
Kenji Okamoto and Yasushi Sako
"Variational Bayes Analysis of a Photon-based Hidden Markov Model for Single-molecule FRET Trajectories"
Biophysical Journal, 2012, 103; 6: 1315–1324.
[doi:10.1016/j.bpj.2012.07.047]
Hiroshima M., Saeki Y., Okada-Hatakeyama M., and Sako Y.
"Dynamically varying interactions between heregulin and ErbB proteins detected by single-molecule analysis in living cells"
Proc. Natl. Acad. Sci. USA, 2012, 109: 13984–13989.
[doi:10.1073/pnas.1200464109]
Pack C., Song M., Lee E.,Hiroshima M., Byun K., Kim J., and Sako Y.
"Microenvironments and different nanoparticle dynamics in living cells revealed by a standard nanoparticle"
Journal of Controlled Release, 2012, 163;315–321.
[doi:10.1016/j.jconrel.2012.07.036]
Ito, M., Shibata, A., Zhang, J., Hiroshima, M., Sako, Y., Nakano, Y., Kojima-Aikawa, K., Mannervik, B., Shuto, S., Ito, Y., Morgenstern, R., and Abe, H.
"Universal caging group for in cell detection of glutathione transferase applied to 19F NMR and bioluminogenic probes"
ChemBioChem, 2012, 9; 13(10): 1428–32.
[doi:10.1002/cbic.201200242]
Shin, H.S., Okamoto, A., Sako, Y., Kim, S. W., Kim, S. Y., and Pack, C.G.:
"Radiationless deactivation of doubly thiazole orange labeled DNA"
Journal of Luminescence, 2012, 132; 2566–2571.
[doi:10.1016/j.jlumin.2012.04.046]
Haga, Y., Ishii, K., Hibino, K., Sako, Y., Ito, Y., Taniguchi, N., and Suzuki, T.
"Visualising specific protein glycoforms by transmembrane fluorescence resonance energy transfer"
Nat. Commun., 2012, 19;3:907.
[doi:10.1038/ncomms1906]
Takahashi, M., Shibata, T., Yanagida, T., and Sako, Y.
"A protein switch with tunable steepness reconstructed in E. coli cells with eukaryoteic signaling proteins"
Biochem. Biophys. Res. Comm., 2012, 18;421:731–735. [doi:10.1016/j.bbrc.2012.04.071]

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2011年

Ishido, N., Kobayashi, H., Sako, Y., Arai, T., Fukuda, M., and Nakamura, T.
How to make FRET biosensors for Rab family GTPases.
Biosensors?Emerging Materials and Applications, pp.81- 98. Serra, P. A. ed. INTECH (2011.3.4)
Sako Y., Hiroshima M., Pack C., Okamoto K., Hibino K., and Yamamoto A.
Live Cell Single-molecule Detection in Systems Biology.
WIREs Syst. Biol. and Med., 2011, 4, 183-192
Komatsuzaki T., Kawakami M., Takahashi S., Yang H., and Silbey R.J. : Okamoto K. and Terazima M.
Quantitative analysis of single-molecule FRET signals and its application to telomere DNA.
Single-Molecule Biophysics:Exp. and Theo., 2011, vol. 146
Hibino, K., Shibata, T., Yanagida, T., and Sako, Y.
Activation kinetics of RAF protein in the Ternary Complex of RAF, RAS-GTP, and kinase on the plasma membrane of living cells.
J. Biol. Chem., 2011, 286, 36460-36468.
Tsuji T., Kawai-Noma S., Pack C., Terajima H., Yajima J., Nishizaka T., Kinjo M., and Taguchi H. (2011)
Single-particle tracking of quantum dot-conjugated proteins inside yeast cells. Biochem. Biophys. Res. Commun. 405, 638-643.
Kurahashi H., Pack C., Shibata S., Oishi K., Sako Y., Nakamura Y. (2011)
[PSI+] aggregate enlargement in rnq1 non-prion domain mutants, leading to a loss-of-prion in yeast. Genes Cells. 16, 576-589.
佐甲靖志 (2011)
細胞内情報処理反応とそのゆらぎ：蛋白質の１分子反応計測　光アライアンス　22, 8-11.
[Book Chaptor] Takagi, H., Morimatsu, M., and Sako, Y. (2011.11.22)
Static and dynamic disorder in in vitro reconstituted receptor/adaptor interaction. “Single-molcule biophysics: experiment and theory”
Adv. Chem. Phys. 146: 195-215. Komatsuzaki, T., Kawakami, M., Takahashi, S., Yang, H., and Silbey, R. J. eds. Wiely.

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2010年

Kawai-Noma S., Pack, C., Kojidani T. Asakawa H., Hiraoka Y., Kinjo, M., and Taguchi H., Hirata A. (2010)
In vivo evidence for the fibrillar structures of Sup35 prions in yeast cells. J. Cell Biol. 190, 223-231.
Pack C. (2010)
Biocompatible nano-agent for diffusional analysis in living cells. Proceedings of Asian Pacific Laser Symposium. 9(10), 107.
日比野佳代、白燦基、佐甲靖志 (2010.3.22)
細胞内１分子計測とシステムズバイオロジー　細胞工学 29, 344-348.
[Book] Sako Y, M and Ueda Editors; Cell Signaling Reactions: Single-Molecular Kinetic Analysis [Hardcover]
[Book Chapter] Michio Hiroshima and Yasushi Sako 2011, Cell Signaling Reactions, Pages 1-32 Single-Molecule Kinetics Analasis of Receptor Protein Tyrosine Kinases
[Book Chapter] Kayo Hibino and Yasushi Sako 2011, Cell Signaling Reactions, Pages 59-78 Single-Molecule Analysis of Molecular Recognition Between Signaling Proteins RAS and RAF

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2009年

Hibino, K., Shibata, T., Yanagida, T., and Sako, Y. (2009)
A RasGTP-induced Conformational Change in C-RAF Essential for Accurate Molecular Recognition. Biophys. J. 97, 1277-1287.
Furukawa, K., Abe, H., Hibino, K., Sako, Y., Tsuneda, S., and Ito, Y. (2009)
Reduction-triggered fluorescent amplification probe for detection of endogenous RNAs in living human cells. Bioconj. Chem. 20(5), 1026-1036.
Hibino, K., Hiroshima, M., Takahashi, M., and Sako, Y. Single-molecule imaging of fluorescent proteins expressed in living cells. (2009)
Methods Mol. Biol. 544, Lee, J. W. ed. Humana Press, 544, 451-60.
Ueda, M., Shibata, T. and Sako, Y. (2009)
Signal transduction across the plasma membrane. “Single Molecule Dyanmics in Life Science”, 99-116. Yanagida, T. and Ishii, Y. ed. WILEY-VCH.
Kawai-Noma S., Pack, C., Tsuji T., Kinjo, M., and Taguchi H. (2009)
Single mother-daughter pair analysis to clarify the diffusion properties of yeast prion Sup35 in guanidine-HCl treated [PSI+] cells. Genes Cells 14, 1045-1054.
佐甲靖志 (2009)
細胞内情報伝達反応の１分子キネティクス　生物物理 49, 184-191.

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2008年

Yumura, S., Ueda, M., Sako, Y., Kitanishi-Yumura, T., and Yanagida, T. (2008)
Multiple mechanisms for accumulation of myosin II filaments at the equator during cytokinesis. Traffic, 9, 2089-2099.
Tanaka, S.-i., Miyata, T., Kato, T., Namba, K., Yanagida, T., Sako, Y., Kawata, S., and Inouye, Y. (2008)
Construction of two color semiconductor Quantum dots wire by utilizing the complementarity of DNA. AIP Conference Proceedings 1062 “DNA-Based Nanodevices”, 116-122.
佐甲靖志 (2008)
細胞内シグナル伝達システムの１分子イメージング「生命現象の動的理解を目指すライブイメージング」宮脇敦史編　実験医学増刊26, 2718-2723.

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2007年

Morimatsu, M., Takagi, H., Ota, K. G., Iwamoto, R., Yanagida, T. and Sako, Y. (2007)
Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed using single-molecule analysis. Proc. Natl. Acad. Sci. USA, 104, 18013-18018.
Miyauchi, T., Yanagida, T., and Sako, Y. (2007)
Rho small GTPase regulates the stability of individual focal adhesions: a FRET-based visualization of GDP/GTP exchange on small GTPases. Biophysics, 3, 63-73.
佐甲靖志 (2007)
細胞内情報伝達分子間相互作用の１分子可視化解析「特集・分子イメージング」顕微鏡 42, 166-169.
佐甲靖志 (2007)
１分子イメージングによる解析法「分子間相互作用ハンドブック」磯部俊明、中山敬一、伊藤隆司編 pp.96-100　羊土社
佐甲靖志 (2007)
全反射顕微鏡と１分子計測「生細胞蛍光イメージング」原口徳子、木村宏、平岡泰編 pp.206-220　共立出版
日比野佳代・佐甲靖志 (2007)
全反射顕微鏡による１分子動態観察「生細胞蛍光イメージング」原口徳子、木村宏、平岡泰編 pp.291-294　共立出版

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2006年

Murai, T., Miyauchi, T., Yanagida. T. and Sako, Y. (2006)
Epidermal growth factor-regulated activation of Rac GTPase enhances CD44 cleavage by metalloproteinase disintegrin ADAM10. Biochem. J. 395, 65-71.
Shibata, S. C., Hibino, K., Mashimo, T., Yanagida, T. and Sako, Y. (2006)
Formation of signal transduction complexes during immobile phase of NGFR movements. Biochem. Biophys. Res. Comm. 342, 316-322.
Ichinose, J., Morimatsu, M., Yanagida, T. and Sako, Y. (2006)
Covalent immobilization of epidermal growth factor molecule for single-molecule imaging analysis of intracellular signaling. Biomaterials 27, 3343-3350.
Prashar, V., Capalash, N., Xu, S-y., Sako, Y. and Sharma, P. (2006)
TspMI, a thermostable isoschizomer of XmaI (5’C/CCGGG3’): characterization and single molecule imaging with DNA. App. Microbiol. Biotechnol. 72, 917-923.
Teramura, Y., Ichinose, J., Takagi, H., Nishida, K., Yanagida, T. and Sako, Y. (2006)
Single-molecule analysis of epidermal growth factor binding on the surface of living cells. EMBO J. 25, 4215-4222.
Tanaka, S, Fritzsche, W., Sako, Y. and Yanagida, T. (2006)
Synthesis of long-template DNA using enzymatic reaction for regular alignment of Au-nanoparticles. Chem. Lett. 35, 1290-1291.
Sako, Y. (2006)
Imaging single molecules for systems biology. Mol. Syst. Biol. doi:10.1038/msb4100100.
佐甲靖志 (2006)
生細胞における１分子キネティクス　物性研究　85, 668-684.
日比野佳代、佐甲靖志 (2006) 情報伝達蛋白質Ras, Raf1相互作用のダイナミクスとキネティクス　物性研究 86, 46-51.
佐甲靖志 (2006)
細胞内蛍光１分子可視化法（基礎編）「現場で役立つバイオイメージング」バイオニクス 3-6, 72-76.
佐甲靖志、日比野佳代 (2006)
細胞内蛍光１分子可視化法（応用編）「現場で役立つバイオイメージング」バイオニクス 3-7, 72-76.

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2005年

Tani, T., Miyamoto, Y., Fujimori, K., Taguchi, T., Yanagida, T., Sako, Y. and Harada, Y. (2005)
Trafficking of ligand-receptor complex on the growth cones as an essential step for the uptake of nerve growth factor at the distal end of the axon: a single-molecule analysis. J. Neurosci. 25, 2181-2191.
Uyemura, T., Takagi, H., Yanagida, T. and Sako, Y. (2005)
Single-molecule analysis of epidermal growth factor signaling that leads to ultrasensitive calcium response. Biophys. J. 88, 3720-3730.
岩根敦子、上田昌宏、日比野佳代、佐甲靖志、柳田敏雄 (2005)
情報伝達分子の生細胞イメージング　「シグナル伝達研究2005-'06」山本雅、仙波憲太郎編　実験医学増刊23, 1976-1802.
佐甲靖志 (2005)
細胞内蛍光１分子観察法とその応用「光科学研究の最前線」「光科学研究の最前線」発行委員会編 pp.388-389 強光子場科学研究懇談会

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2004年

Murai, T., Miyazaki, Y., Nishinakamura, H., Sugahara, K. N., Miyauchi, T., Sako, Y., Yanagida, T., and Miyasaka, M. (2004)
Engagement of CD44 promotes Rac activation and CD44 cleavage during tumor cell migration. J. Biol. Chem., 279, 4541-4550.
Ichinose, J., Murata, M., Yanagida, T. and Sako, Y. (2004)
Single molecule observation of amplification of EGF receptor activation in semi-intact A431 cells. Bichem. Biophys. Res. Commun. 324, 1143-1149.
Ichinose, J. and Sako, Y. (2004)
Single-molecule measurement in living cells. Trends Anal. Chem. 23. 587-594.
森松美紀、佐甲靖志 (2004)
１分子計測法による細胞内分子システムの解析　BME 18, 19-26.
佐甲靖志 (2004)
光ピンセット「バイオ高性能機器・新技術利用マニュアル」小原収、谷口寿章、市川哲生、猪飼篤　編　蛋白質・核酸・酵素増刊49, 1615-1619.
堺立也、山科正平、佐甲靖志 (2004)
エンドサイトーシス実験法（エンドソーム観察法）「細胞生物学実験法III-I」大熊勝治編集 pp.18-32　広川書店
佐甲靖志 (2004)
細胞内情報処理システムを１分子計測する「〈１分子〉生物学　生命システムの新しい理解」合原一幸、岡田康志編　pp.43-81　岩波書店
佐甲靖志 (2004)
ナノテクノロジー「医学を学ぶための生物学」谷口直之、米田悦啓編　pp.429-436　南江堂

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2003年

Hibino, K., Watanabe, T., Kozuka, J., Iwane, A. H., Okada, T., Kataoka, T., Yanagida, T., and Sako, Y. (2003)
Single- and multiple-molecule dynamics of the signaling from H-Ras to c-Raf1 visualized on the plasma membrane of living cells. Chem. Phys. Chem., 4, 748-753.
Sako, Y. and Yanagida, T. (2003)
Single-molecule visualization in cell biology. Nature Rev. Mol. Cell Biol. 4, SS1-5.
Sako, Y., Ichinose, J., Morimatsu, M., Ohta, K., and Uyemura, T. (2003)
Single-molecule visualization of cell signaling processes of epidermal growth factor receptor. J. Pharmacol. Sci., 93, 253-258.
佐甲靖志 (2003)
細胞内情報処理過程の１分子観察　生理学会誌　65, 277-282.
上田昌宏、佐甲靖志 (2003)
１分子と細胞「ナノテクノロジーハンドブック　IV編　バイオ・化学へ使う」ナノテクノロジーハンドブック編集委員会編pp.123-127オーム社

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2002年

Sako, Y. and Uyemura, T. (2002)
Total internal reflection fluorescence microscopy for single-molecule imaging in living cells. Cell Struct. Funct., 27, 357-365.
Sako, Y. (2002)
Imaging of biological molecules. 2. Membrane receptors. in "Nano-Optics" Kawata, S., Ohtsu, M., and Irie, M. ed. pp.209-215. Springer.
佐甲靖志 (2002)
一分子イメージング　医学のあゆみ　200, 1092
上田昌宏、佐甲靖志 (2002)
GPCR型走化性受容体の細胞内１分子可視化解析「バイオイメージングでここまで理解る」楠見明弘、小林剛、吉村昭彦、徳永万喜洋編　実験医学別冊　pp.99-103.
宮内崇行、日比野佳代、佐甲靖志 (2002)
蛍光共鳴エネルギー移動のイメージング「シリーズ・バイオサイエンス新世紀　第12巻　感覚器官と脳内情報処理」御子柴克彦、清水孝雄編　共立出版　pp.210-217.

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2001年

Ueda, M., Sako, Y., Tanaka, T., Devreotes, P. N., and Yanagida, T. (2001)
Single molecule analysis of chemotactic signaling in Dictyostelium cells. Science, 294, 864-867.
佐甲靖志 (2001)
上皮成長因子受容体の１分子反応計測　細胞工学　20, 678-682.

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2000年

Sako, Y., Minoguchi, S., and Yanagida, T. (2000)
Single molecule imaging of EGFR signal trasnduction on the living cell surface. Nature Cell Biol. 2, 168-172.
Kano, F., Sako, Y., Tagaya, M., Yanagida, T., and Murata, M. (2000)
Reconstitution of brefeldin A-induced Golgi-tubulation and fusion with the endoplasmic reticulum in semi-intact Chinese hamster ovary cells. Mol. Biol. Cell, 11, 3073-3087.
Sako, Y., Hibino, K., Miyauchi, T., Miyamoto, Y., Ueda, M., and Yanagida, T. (2000)
Single-molecule imaging of signaling molecules in living cells. Single Mol., 1, 151-155.
Yanagida, T., Tanaka, H., Kitamura, K., Wazawa, T., Nishiyama, M., Esaki, S., Sako, Y., Ide, T., Iwane, A. H-, Ishii, Y. (2000)
Single molecule techniques in biophysics. "Na/K-ATPase and related ATPases" Taniguchi, K. and Kaya, S. ed. pp. 71-85. Elsevier Science
佐甲靖志、箕口滋、柳田敏雄 (2000)
EGF受容体の動態の細胞内１分子画像測定　細胞工学　19, 1184-1186.
佐甲靖志 (2000)
細胞膜蛋白質と膜骨格・細胞骨格の相互作用　?細胞膜の構造形成?「シリーズ・ニューバイオフィジックスII　第４巻　生体膜のダイナミクス」八田一郎、村田昌之編　共立出版　pp.139-156.

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2000年まで

佐甲靖志 (1999)
膜骨格による細胞膜タンパク質の運動制御　生物物理　221, 10-13.
藤崎久雄、佐甲靖志 (1999)
多光子励起顕微鏡と全反射顕微鏡によるバイオロジー　分光研究　48, 260-267.
Sako, Y., Nagafuchi, A., Tsukita, S., Takeichi, M., and Kusumi, A. (1998)
Cytoplasmic regulation of the movement of E-cadherin on the free cell surface as studied by optical tweezers and single particle tracking : corralling and tethering by the membrane skeleton. J. Cell Biol., 140, 1227-1240.
Takeuchi, M., Miyamoto, H., Sako, Y., Komizu, H., and Kusumi, A. (1998)
Structure of the erythrocyte membrane skeleton as observed by atomic force microscopy. Biophys. J., 74, 2171-2183.
Tomishige, M., Sako, Y., and Kusumi, A. (1998)
Regulation mechanism of the lateral diffusion of band 3 in erythrocyte membranes by the membrane skeleton. J. Cell Biol., 142, 989-1000.
Kusumi, A., Sako, Y., Fujiwara, T., and Tomishige, M. (1998)
Application of laser tweezers to studies of the fences and tethers of the membrane skeleton which regulate the movements of plasma membrane proteins. Method. Cell Biol. 55, "Laser Tweezers in Cell Biology", pp.174-194. Sheetz, M. P. ed. Academic Press
佐甲靖志 (1998)
２光子励起レーザー走査蛍光顕微鏡法　電子顕微鏡　33, 122-124.
佐甲靖志 (1998)
多光子励起蛍光顕微鏡法の細胞内情報伝達研究への応用「カルシウムイオンとシグナル伝達」、御子柴克彦、遠藤　實、宮本栄七編　蛋白質核酸酵素43, 増刊　pp.1927-1930.
佐甲靖志 (1998)
２光子励起蛍光顕微鏡法の生物学への応用「電子顕微鏡　基礎技術と応用1998」第９回電顕サマースクール実行委員会編　学際企画　pp.150-154.
Sako, Y., Sekihata, A., Yanagisawa, Y., Yamamoto, M., Shimada, Y., Ozaki, K., and Kusumi, A. (1997)
Comparison of two-photon excitation laser scanning microscopy with UV-confocal laser scanning microscopy in 3-dimensional calcium imaging using the fluorescence indicator Indo-1. J. Micros., 185, 9-20.
佐甲靖志 (1997)
レーザー光解剖とレーザー光ピンセットの原理　遺伝51, 16-20.
佐甲靖志 (1997)
膜蛋白質分子を操る　遺伝　51, 21-25.
楠見明弘　佐甲靖志 (1997)
２光子励起蛍光顕微鏡「見る技術　分子・細胞のバイオイメージング」、石川春律、鈴木和男、中西　守、猪飼　篤編　蛋白質核酸酵素42, 増刊　pp.1151-1153.
佐甲靖志 (1997)
細胞膜蛋白質の結合した細胞骨格・膜骨格系の力学応答 Space Utilization Research, 14, 110-113.
Kusumi, A. and Sako, Y. (1996)
Cell surface organization by the membrane skeleton. Curr. Opin. Cell Biol., 8, 566-574.
佐甲靖志、富重道雄、藤原敬宏 (1996)
光ピンセット法とその細胞膜研究への応用　ファルマシア　32, 271-275.
佐甲靖志 (1996)
光学顕微鏡で見る分子の世界「電子顕微鏡　基礎技術と応用1996」第７回電顕サマースクール実行委員会編　学際企画　pp.135-142.
Sako, Y. and Kusumi, A. (1995)
Barriers for lateral diffusion of transferrin receptors in the plasma membrane as characterized by receptor dragging by laser tweezers: fence versus tether. J. Cell Biol., 129, 1559-1574.
佐甲靖志 (1995)
光ピンセット法　日本バイオイメージング学会会報 8, 1-5.
佐甲靖志 (1995)
２光子励起蛍光顕微鏡「新しい光学顕微鏡　第２巻　共焦点レーザー顕微鏡の医学・生物学への応用」藤田晢也監修　石川春律、高松哲郎編　学際企画　pp.20-25.
Sako, Y. and Kusumi, A. (1994)
Compartmentalized structure of the plasma membrane for receptor movements as revealed by a nanometer-level motion analysis. J. Cell Biol., 125, 1251-1264.
佐甲靖志 (1994)
レーザー光ピンセット法とその応用　細胞26, 431-436.
Oida, T., Sako, Y., and Kusumi, A. (1993)
Fluorescence lifetime imaging microscopy (flimscopy). Methodology development and application to studies of endosome fusion in single cells. Biophys. J., 64, 676-685.
Kusumi, A., Sako, Y., and Yamamoto, M. (1993)
Confined lateral diffusion of membrane receptors as studied by single particle tracking (nanovid microscopy). Effects of calcium-induced differentiation in cultured epithelial cells. Biophys. J., 65, 2021-2040.
楠見明弘、佐甲靖志、藤原敬宏 (1993)
細胞膜タンパク質の運動、会合、集合と機能「Annual Review 細胞生物学 1993」pp.86-106. 矢原一郎、御子柴克彦、月田承一郎編　中外医学社
佐甲靖志、楠見明弘 (1992)
分子運動の直接観察による細胞膜のドメイン構造の研究表面 30, 44-51.
佐甲靖志、楠見明弘 (1992)
膜タンパク質の拡散運動の制御機構：単一粒子追跡法による研究　物理学会誌　47, 806-809.
佐甲靖志、楠見明弘 (1992)
E-カドヘリンの細胞膜上での運動の制御機構　実験医学増刊「細胞接着の分子機構?形態形成・免疫・癌への展開」pp.61-67. 月田承一郎、宮坂昌之、鈴木信太郎編集　羊土社
Kusumi, A., Tsuji, A., Murata, M., Sako, Y., Yoshizawa, A. C., Kagiwada, S., Hayakawa, T., and Ohnishi, S. (1991)
Development of a streak-camera-based time-resolved microscope fluorimeter and its application to the studies of membrane fusion in single cells. Biochemistry, 30, 6517-6527.
楠見明弘、佐甲靖志、種田貴徳 (1991)
蛍光寿命イメージング???ＦＬＩＭ．細胞工学　10, 79-84.
山本睦也、佐甲靖志、楠見明弘 (1991)
ナノメートル計測による細胞接着レセプター・カドヘリンの動態の解析　Cell Science 7, 400-407.
Sako, Y., Sato, S. B., and Ohnishi, S. (1990)
Subpopulations of endosomes generated at sequential stages in the endocytic pathway of asialoganglioside-containing ferrite ligands in rat liver. J. Biochem. 107, 846-853.
Kusumi, A., Tsuji, A., Murata, M., Sako, Y., Kagiwada, S. and Ohnishi, S. (1990)
Development of time-resolved microfluorimetry and its application to cellular membranes. SPIE proc. 1204, "Time-resolved laser spectroscopy in biochemistry II." 776-783.
佐甲靖志、堺　立也、大橋正人、大西俊一 (1989)
エンドソームにおけるリガンドと受容体の選別　細胞工学8, 163-171.
佐甲靖志、楠見明弘 (1989)
時間分解顕微蛍光法：培養細胞中のエンドソーム膜融合の研究への応用　細胞工学 8, 554-560.
村田昌之、鍵和田聡、佐甲靖志 (1989)
膜小胞化と膜融合　細胞21, 416-420.
Kusumi, A., Tsuji, A., Murata, M., Sako, Y., Yoshizawa, A. C., Hayakawa, T., and Ohnishi, S. (1988)
Development of a time-resolved micro-fluorimeter with a syncroscan streak camera and its application to studies of cell membranes. SPIE proc. 909, "Time-resolved laser spectroscopy in biochemistry." 350-351.
Sato, S. B., Sako, Y., Yamashina, S., and Ohnishi, S. (1986)
A novel method for isolating specific endocytic vesicles using very fine ferrite particles coated with biological ligands and the high-gradient magnetic separation technique. J. Biochem. 100, 1418-1492.

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